We expect ME Andromeda to run well on high end PCs. To reach recommended requirements you will need at least a GTX 670 or R9 280 GPU. If this is paired with a mid ranged Intel i5 or Phenom II AMD processor and 8GB of system memory then you should be able to play Mass Effect Andromeda at 50-65 FPS on high graphics settings and 1920x1080 screen resolution. Lower specced machines, like a GTX 650 ti or HD 6850 GPU would probably be able to get around 30 FPS at 900p resolution on low graphics settings.
Mass Effect Andromeda is the beginning of an all-new saga in the Mass Effect universe. The remnants of mankind make their way to the Andromeda galaxy in an effort to forge in new life in Bioware's epic sci-fi RPG.