Protect the core against the damaging particles as long as you can. Stand still agains several kinds of particles that will try to trick or overwhelm you. Show them you're up to your task, and reach the endless Sixth Risk Level.
Core Meltdown requires at least a Radeon X1900 GT or GeForce GT 340 to meet recommended requirements running on high graphics setting, with 1080p resolution. This hardware should achieve 60FPS. To summarise, Core Meltdown needs around a 9 year old PC to play at recommended settings.