The game begins with Reed, Sue, and Johnny on a roof lying helpless after being knocked unconscious by a blast from Dr. Doom. Sue is the first to recover, so when she sits up and turns around, Dr. Doom is preparing to fire an electric blast at them. Sue holds it off with her force field and calls ben Grimm for help. Then it cuts away to Ben, who is recovering in the transformation chamber after having his rocklike exterior genetically removed from him. As he contemplates why the circumstances have led to this, he remembers the period when all of this happens. This is when it reverts to the beginning of the movie: Reed signs the pact, they go into space, and Ben gets the samples ready. In space, they are hit by a cosmic storm which alters their DNA and gives them superpowers. If it hadn't been for Victor, they might never have arrived back to Earth and into his medical compound, where they recovered. When Ben discovers that he has become a monster-like figure, he deserts the other three and heads home.
Fantastic 4 requires a Radeon 9000 Series 64MB graphics card with a Pentium 4 1.4GHz or Athlon XP 1700+ processor to reach the recommended specs, achieving high graphics setting on 1080p. The RAM requirements are at least a 512 MB memory. Finally, Fantastic 4 will need hardware that is a 17 year old PC or younger to run recommended.