Lollipop Chainsaw focuses on zombie hunter and cheerleader Juliet Starling (voiced by Tara Strong) who, along with members of her family and her boyfriend, a disembodied head, fight hordes of zombies in San Romero High School, where Starling formerly cheered. The enemy zombies are led by "a group of zombie rock and roll lords". The zombies are led by Juliet's evil goth classmate/powerful sorcerer, Swan.