The Binding of Isaac: Repentance GPU Analysis
Comparing The Binding of Isaac: Repentance PC system requirements to all GPUs shows that The Binding of Isaac: Repentance is going to need a graphics card that is capable of OpenGL 4.2.

To get the best visual graphical experience on The Binding of Isaac: Repentance, aim to have a GPU that has at least 2GB GPU RAM.

Only top performance graphics cards currently available today, will probably allow you to play The Binding of Isaac: Repentance

We are advised that 8 year old graphics cards should be able to run The Binding of Isaac: Repentance, but there could be a few exceptions to this rule.

Note that most games do not officially support laptop graphics cards, but nowadays many laptop graphics solutions are capable of running modern games. Whether desktop graphics cards or laptop, try searching for your graphics card to compare against the The Binding of Isaac: Repentance graphics card requirements chart below.