Ms. Splosion Man shares much of the same gameplay with its predecessor, 'Splosion Man. The character is made entirely of explosive material. The aim of the game is to "splode" through a series of levels consisting of puzzles, traps, and enemies to escape the facility. A splode is effectively a jump, and can also be used to kill enemies, such as scientists and robots, demolish walls, detonate explosive barrels or trigger other effects.