Duke Nukem: Mass Destruction GPU Analysis
Comparing Duke Nukem: Mass Destruction PC system requirements to all GPUs shows that Duke Nukem: Mass Destruction is going to need a graphics card that is capable of OpenGL 2.1.

To get the best visual graphical experience on Duke Nukem: Mass Destruction, aim to have a GPU that has at least 512MB GPU RAM.

Most bottom end graphics cards currently available today, will probably allow you to play Duke Nukem: Mass Destruction

We are advised that 14 year old graphics cards should be able to run Duke Nukem: Mass Destruction, but there could be a few exceptions to this rule.

Note that most games do not officially support laptop graphics cards, but nowadays many laptop graphics solutions are capable of running modern games. Whether desktop graphics cards or laptop, try searching for your graphics card to compare against the Duke Nukem: Mass Destruction graphics card requirements chart below.