In terms of overall gaming performance, the graphical capabilities of the AMD FirePro D300 are noticeably better than the Nvidia GeForce GTX 465.

The FirePro D300 has a 168 MHz higher core clock speed and 36 more Texture Mapping Units than the GeForce GTX 465. This results in the FirePro D300 providing 35.3 GTexel/s better texturing performance. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The FirePro D300 has a 168 MHz higher core clock speed than the GeForce GTX 465 and the same number of Render Output Units. This results in the FirePro D300 providing 5.4 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The FirePro D300 was released over three years more recently than the GeForce GTX 465, and so the FirePro D300 is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the GeForce GTX 465 when running the latest games.

The FirePro D300 has 1024 MB more video memory than the GeForce GTX 465, so is likely to be much better at displaying game textures at higher resolutions. This is supported by the fact that the FirePro D300 also has superior memory performance overall.

The FirePro D300 has 57.3 GB/sec greater memory bandwidth than the GeForce GTX 465, which means that the memory performance of the FirePro D300 is much better than the GeForce GTX 465.

The FirePro D300 has 1280 Shader Processing Units and the GeForce GTX 465 has 352. However, the actual shader performance of the FirePro D300 is 645 and the actual shader performance of the GeForce GTX 465 is 427. The FirePro D300 having 218 better shader performance and an altogether better performance when taking into account other relevant data means that the FirePro D300 delivers a significantly smoother and more efficient experience when processing graphical data than the GeForce GTX 465.

The FirePro D300 transistor size technology is 12 nm (nanometers) smaller than the GeForce GTX 465. This means that the FirePro D300 is expected to run slightly cooler and achieve higher clock frequencies than the GeForce GTX 465.

The FirePro D300 requires 150 Watts to run and the GeForce GTX 465 requires 200 Watts. We would recommend a PSU with at least 500 Watts for the FirePro D300 and a PSU with at least 550 Watts for the GeForce GTX 465. The GeForce GTX 465 requires 50 Watts more than the FirePro D300 to run. The difference is significant enough that the GeForce GTX 465 may have a slight adverse affect on your yearly electricity bills in comparison to the FirePro D300.