In terms of overall gaming performance, the graphical capabilities of the Nvidia Quadro K4200 are noticeably better than the Nvidia GeForce GTX 465.

The Quadro K4200 has a 99 MHz higher core clock speed and 68 more Texture Mapping Units than the GeForce GTX 465. This results in the Quadro K4200 providing 52.4 GTexel/s better texturing performance. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The Quadro K4200 has a 99 MHz higher core clock speed than the GeForce GTX 465 and the same number of Render Output Units. This results in the Quadro K4200 providing 3.2 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The Quadro K4200 was released over three years more recently than the GeForce GTX 465, and so the Quadro K4200 is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the GeForce GTX 465 when running the latest games.

The Quadro K4200 has 3072 MB more video memory than the GeForce GTX 465, so is likely to be much better at displaying game textures at higher resolutions. This is supported by the fact that the Quadro K4200 also has superior memory performance overall.

The Quadro K4200 has 70.1 GB/sec greater memory bandwidth than the GeForce GTX 465, which means that the memory performance of the Quadro K4200 is much better than the GeForce GTX 465.

The Quadro K4200 has 1344 Shader Processing Units and the GeForce GTX 465 has 352. However, the actual shader performance of the Quadro K4200 is 949 and the actual shader performance of the GeForce GTX 465 is 427. The Quadro K4200 having 522 better shader performance and an altogether better performance when taking into account other relevant data means that the Quadro K4200 delivers a massively smoother and more efficient experience when processing graphical data than the GeForce GTX 465.

The Quadro K4200 transistor size technology is 12 nm (nanometers) smaller than the GeForce GTX 465. This means that the Quadro K4200 is expected to run slightly cooler and achieve higher clock frequencies than the GeForce GTX 465.

The Quadro K4200 requires 108 Watts to run and the GeForce GTX 465 requires 200 Watts. We would recommend a PSU with at least 500 Watts for the Quadro K4200 and a PSU with at least 550 Watts for the GeForce GTX 465. The GeForce GTX 465 requires 92 Watts more than the Quadro K4200 to run. The difference is significant enough that the GeForce GTX 465 may have an adverse affect on your yearly electricity bills in comparison to the Quadro K4200.