In terms of overall gaming performance, the graphical capabilities of the Nvidia Quadro 4000 are noticeably better than the AMD Radeon R7 240 2GB.

The R7 240 has a 255 MHz higher core clock speed than the Quadro 4000, but the Quadro 4000 has 12 more Texture Mapping Units than the R7 240. As a result, the Quadro 4000 exhibits a 0.6 GTexel/s better Texture Fill Rate than the R7 240. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The R7 240 has a 255 MHz higher core clock speed than the Quadro 4000, but the Quadro 4000 has 24 more Render Output Units than the R7 240. As a result, the Quadro 4000 exhibits a 9.4 GPixel/s better Pixel Fill Rate than the R7 240. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The R7 240 was released over a year more recently than the Quadro 4000, and so the R7 240 is likely to have better driver support, meaning it will be more optimized for running the latest games when compared to the Quadro 4000.

The Radeon R7 240 2GB and the Quadro 4000 have the same amount of video memory, but are likely to provide slightly different experiences when displaying game textures at high resolutions.

The Quadro 4000 has 61.1 GB/sec greater memory bandwidth than the R7 240, which means that the memory performance of the Quadro 4000 is much better than the R7 240.

The Radeon R7 240 2GB has 320 Shader Processing Units and the Quadro 4000 has 256. However, the actual shader performance of the R7 240 is 212 and the actual shader performance of the Quadro 4000 is 243. The Quadro 4000 having 31 better shader performance and an altogether better performance when taking into account other relevant data means that the Quadro 4000 delivers a significantly smoother and more efficient experience when processing graphical data than the R7 240.

The R7 240 transistor size technology is 12 nm (nanometers) smaller than the Quadro 4000. This means that the R7 240 is expected to run slightly cooler and achieve higher clock frequencies than the Quadro 4000.

The Radeon R7 240 2GB requires 30 Watts to run and the Quadro 4000 requires 142 Watts. We would recommend a PSU with at least 400 Watts for the R7 240 and a PSU with at least 500 Watts for the Quadro 4000. The Quadro 4000 requires 112 Watts more than the R7 240 to run. The difference is significant enough that the Quadro 4000 may have an adverse affect on your yearly electricity bills in comparison to the R7 240.