In terms of overall gaming performance, the graphical capabilities of the AMD FirePro M5100 are very slightly better than the Nvidia GeForce GT 750M 2GB GDDR5.

The GT 750M has a 216 MHz higher core clock speed but 8 fewer Texture Mapping Units than the FirePro M5100. The lower TMU count doesn't matter, though, as altogether the GT 750M manages to provide 1.1 GTexel/s better texturing performance. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The GT 750M has a 216 MHz higher core clock speed than the FirePro M5100 and the same number of Render Output Units. This results in the GT 750M providing 3.5 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The FirePro M5100 was released less than a year after the GT 750M, and so they are likely to have similar driver support for optimizing performance when running the latest games.

The FirePro M5100 and the GeForce GT 750M 2GB GDDR5 have the same amount of video memory, but are likely to provide slightly different experiences when displaying game textures at high resolutions.

The FirePro M5100 has 8 GB/sec greater memory bandwidth than the GT 750M, which means that the memory performance of the FirePro M5100 is marginally better than the GT 750M.

The FirePro M5100 has 640 Shader Processing Units and the GeForce GT 750M 2GB GDDR5 has 384. However, the actual shader performance of the FirePro M5100 is 496 and the actual shader performance of the GT 750M is 406. The FirePro M5100 having 90 better shader performance and an altogether better performance when taking into account other relevant data means that the FirePro M5100 delivers a marginally smoother and more efficient experience when processing graphical data than the GT 750M.

The FirePro M5100 requires 50 Watts to run and the GeForce GT 750M 2GB GDDR5 requires 50 Watts. The two GPUs require the same amount of wattage to run. As such, there is no need to worry about which will more significantly affect your yearly electricity bills.