In terms of overall gaming performance, the graphical capabilities of the Nvidia GeForce 6150 SE 256MB are massively better than the AMD Radeon RX Vega Core 4GB.

The RX Vega was released over three years more recently than the 6150 SE, and so the RX Vega is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the 6150 SE when running the latest games.

Both GPUs exhibit very poor performance, so rather than upgrading from one to the other you should consider looking at more powerful GPUs. Neither of these will be able to run the latest games in any playable way.

The RX Vega has 3840 MB more video memory than the 6150 SE, so is likely to be much better at displaying game textures at higher resolutions. This is supported by the fact that the RX Vega also has superior memory performance overall.

The RX Vega has 256 GB/sec greater memory bandwidth than the 6150 SE, which means that the memory performance of the RX Vega is massively better than the 6150 SE.

The Radeon RX Vega Core 4GB has 4096 Shader Processing Units and the GeForce 6150 SE 256MB has 2. However, the actual shader performance of the RX Vega is 3994 and the actual shader performance of the 6150 SE is 1. The RX Vega having 3993 better shader performance and an altogether better performance when taking into account other relevant data means that the RX Vega delivers a massively smoother and more efficient experience when processing graphical data than the 6150 SE.

The Radeon RX Vega Core 4GB requires 275 Watts to run but there is no entry for the GeForce 6150 SE 256MB. We would recommend a PSU with at least 600 Watts for the RX Vega.