In terms of overall gaming performance, the graphical capabilities of the AMD Radeon RX 5600 6GB are significantly better than the Nvidia GeForce GTX 780.

The RX 5600 has a 267 MHz higher core clock speed than the GeForce GTX 780, but the GeForce GTX 780 has 64 more Texture Mapping Units than the RX 5600. As a result, the GeForce GTX 780 exhibits a 21.1 GTexel/s better Texture Fill Rate than the RX 5600. This still holds weight but shader performance is generally more relevant, particularly since both of these GPUs support at least DirectX 10.

The RX 5600 has a 267 MHz higher core clock speed and 16 more Render Output Units than the GeForce GTX 780. This results in the RX 5600 providing 30.9 GPixel/s better pixeling performance. However, both GPUs support DirectX 9 or above, and pixeling performance is only really relevant when comparing older cards.

The RX 5600 was released over three years more recently than the GeForce GTX 780, and so the RX 5600 is likely to have far better driver support, meaning it will be much more optimized and ultimately superior to the GeForce GTX 780 when running the latest games.

Both GPUs exhibit very powerful performance, so it probably isn't worth upgrading from one to the other, as both are capable of running even the most demanding games at the highest settings.

The RX 5600 has 3072 MB more video memory than the GeForce GTX 780, so is likely to be much better at displaying game textures at higher resolutions. However, overall, the GeForce GTX 780 has superior memory performance.

The GeForce GTX 780 has 0.4 GB/sec greater memory bandwidth than the RX 5600, which means that the memory performance of the GeForce GTX 780 is marginally better than the RX 5600.

The Radeon RX 5600 6GB has 2048 Shader Processing Units and the GeForce GTX 780 has 2304. However, the actual shader performance of the RX 5600 is 2077 and the actual shader performance of the GeForce GTX 780 is 2078. The GeForce GTX 780 having 1 better shader performance is not particularly notable, as altogether the RX 5600 performs better when taking into account other relevant data.

The RX 5600 transistor size technology is 21 nm (nanometers) smaller than the GeForce GTX 780. This means that the RX 5600 is expected to run slightly cooler and achieve higher clock frequencies than the GeForce GTX 780.

The Radeon RX 5600 6GB requires 150 Watts to run and the GeForce GTX 780 requires 250 Watts. We would recommend a PSU with at least 550 Watts for the RX 5600 and a PSU with at least 600 Watts for the GeForce GTX 780. The GeForce GTX 780 requires 100 Watts more than the RX 5600 to run. The difference is significant enough that the GeForce GTX 780 may have an adverse affect on your yearly electricity bills in comparison to the RX 5600.