In terms of overall gaming performance, the graphical capabilities of the Nvidia GeForce 6150 SE 256MB are noticeably better than the Nvidia Quadro NVS 280.

The 6150 SE was released over a year more recently than the Quadro NVS 280, and so the 6150 SE is likely to have better driver support, meaning it will be more optimized for running the latest games when compared to the Quadro NVS 280.

Both GPUs exhibit very poor performance, so rather than upgrading from one to the other you should consider looking at more powerful GPUs. Neither of these will be able to run the latest games in any playable way.

The 6150 SE has 192 MB more video memory than the Quadro NVS 280, so is likely to be slightly better at displaying game textures at higher resolutions. This is supported by the fact that the 6150 SE also has superior memory performance overall.

The memory bandwidth of the Quadro NVS 280 and the GeForce 6150 SE 256MB are the same, which means the Quadro NVS 280 and the 6150 SE have equal limitations when it comes to graphical data transfer.

The Quadro NVS 280 has 1 Shader Processing Units and the GeForce 6150 SE 256MB has 2. However, the actual shader performance of the Quadro NVS 280 is 0 and the actual shader performance of the 6150 SE is 1. The 6150 SE having 1 better shader performance and an altogether better performance when taking into account other relevant data means that the 6150 SE delivers a marginally smoother and more efficient experience when processing graphical data than the Quadro NVS 280.